MALDI-TOF MS Characterization of Carboxyl-End-Capped Polystyrenes Synthesized Using Anionic Polymerization

MALDI-TOF MS Characterization of Carboxyl-End-Capped Polystyrenes Synthesized Using Anionic Polymerization

A comparative study of three strategies used to synthesize well-defined carboxyl-end-capped polystyrenes is reported. Structural characterization was carried out using a combination of thin-layer chromatography (TLC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). For the reaction of polystyryl anions with 4-bromo-1,1,1-trimethoxybutane, in addit...

Characterization of fengycin homologues produced by Bacillus subtilis K1 by MALDI-TOF tandem mass spectrometry (MALDI TOF MS/MS)

Using MALDI-TOF-MS to test Staphylococcus aureus–infected vitreous

PURPOSE This study aimed to establish a method for testing Staphylococcus aureus in the vitreous of endophthalmitis with matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS), which is simple, fast, and sensitive. METHODS S. aureus at different numbers was either mixed with homogenized vitreous or inoculated in porcine eyes for culturing, followed by homo...

MALDI-TOF MS in Prenatal Genomics.

Prenatal diagnosis aims either to provide the reassurance to the couples at risk of having an affected child by timely appropriate therapy or to give the parents a chance to decide the fate of the unborn babies with health problems. Invasive prenatal diagnosis (IPD) is accurate, however, carrying a risk of miscarriage. Non-invasive prenatal diagnosis (NIPD) has been developed based on the exist...

Characterization of a novel Sepia officinalis neuropeptide using MALDI-TOF MS and post-source decay analysis.

A novel neuropeptide acting as a myosuppressor on esophagus, funnel and mantle muscular fibers has been isolated from the stellar ganglia of the mollusk cephalopod Sepia officinalis by means of HPLC analysis. Fractions were monitored using a myotropic bioassay. After three separation steps, MALDI-TOF spectrum revealed one main peak at m/z 756.6. The partial N-terminal and C-terminal digestions ...